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Multiple Choice

Which term is a direct alias for Target cells?

Target cells appear on a blood smear with a bullseye or iris-like appearance due to excess membrane relative to hemoglobin. This extra membrane makes the cell thin and delicate, giving a peripheral ring of hemoglobin with a lighter zone in the middle. Because the cell essentially has more membrane for its volume, it’s described as a leptocyte, another name for the same morphology (codocyte). That direct alias captures the idea of a cell with prominent membrane relative to its content, hence the target look. Other morphologies mentioned are distinct: schistocytes are fragmented RBCs typical of microangiopathic processes; elliptocytes are elongated cells seen in elliptocytosis or iron deficiency; drepanocytes are sickle-shaped cells seen in sickle cell disease.

Target cells appear on a blood smear with a bullseye or iris-like appearance due to excess membrane relative to hemoglobin. This extra membrane makes the cell thin and delicate, giving a peripheral ring of hemoglobin with a lighter zone in the middle. Because the cell essentially has more membrane for its volume, it’s described as a leptocyte, another name for the same morphology (codocyte). That direct alias captures the idea of a cell with prominent membrane relative to its content, hence the target look.

Other morphologies mentioned are distinct: schistocytes are fragmented RBCs typical of microangiopathic processes; elliptocytes are elongated cells seen in elliptocytosis or iron deficiency; drepanocytes are sickle-shaped cells seen in sickle cell disease.