Which statement correctly describes glycophorins?

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Multiple Choice

Which statement correctly describes glycophorins?

Glycophorins are components of the red blood cell membrane that embed in the lipid bilayer as integral membrane proteins. They span the membrane, with an extracellular, heavily glycosylated domain rich in sialic acid that gives the cell its negative surface charge and provides blood group antigen determinants. The short cytoplasmic tail interacts with the spectrin-ankyrin cytoskeleton to help maintain membrane stability and shape. They are not simply loosely attached surface proteins (peripheral) or cytosolic signaling molecules, nor are they secreted extracellular matrix proteins.

Glycophorins are components of the red blood cell membrane that embed in the lipid bilayer as integral membrane proteins. They span the membrane, with an extracellular, heavily glycosylated domain rich in sialic acid that gives the cell its negative surface charge and provides blood group antigen determinants. The short cytoplasmic tail interacts with the spectrin-ankyrin cytoskeleton to help maintain membrane stability and shape. They are not simply loosely attached surface proteins (peripheral) or cytosolic signaling molecules, nor are they secreted extracellular matrix proteins.

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