Which statement about RBC membrane proteins and antigens is true?

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RBC antigens are displayed on the outside of the red cell membrane, attached to components that reside in the plasma membrane. The antigenic determinants are carried by membrane molecules such as glycoproteins and glycolipids, with the outward-facing carbohydrate structures accessible to antibodies. Many of these determinants are on integral membrane proteins that span the membrane, placing the antigenic sites on the external surface. Cytosolic proteins stay inside the cell and are not exposed to circulating antibodies, so they do not carry surface antigens. Secreted proteins would be released away from the membrane, not part of the membrane-bound antigen presentation. In short, surface antigens are tied to membrane-bound proteins or lipids with outward-facing determinants, not to cytosolic components.