Which stage has a size of 14-20 μm?

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Multiple Choice

Which stage has a size of 14-20 μm?

In erythropoiesis, cells start large and shrink as they mature. The largest erythroid precursor is the rubriblast (pronormoblast), which measures roughly 14–20 μm in diameter and has a very large nucleus with a high nucleus-to-cytoplasm ratio and basophilic cytoplasm. As maturation progresses to prorubricyte and then rubricyte, the cells become progressively smaller as chromatin condenses and hemoglobin synthesis begins in earnest. Reticulocytes, released into the bloodstream, are even smaller (closer to mature red blood cell size). Because 14–20 μm is characteristic of the early, largest precursor, the stage that fits this size range is rubriblast.

In erythropoiesis, cells start large and shrink as they mature. The largest erythroid precursor is the rubriblast (pronormoblast), which measures roughly 14–20 μm in diameter and has a very large nucleus with a high nucleus-to-cytoplasm ratio and basophilic cytoplasm. As maturation progresses to prorubricyte and then rubricyte, the cells become progressively smaller as chromatin condenses and hemoglobin synthesis begins in earnest. Reticulocytes, released into the bloodstream, are even smaller (closer to mature red blood cell size). Because 14–20 μm is characteristic of the early, largest precursor, the stage that fits this size range is rubriblast.

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