Which additive is used together with lithium iodoacetate?

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Multiple Choice

Which additive is used together with lithium iodoacetate?

Glycolysis inhibition and anticoagulation must work together to preserve a true glucose level in a blood sample. Lithium iodoacetate acts as an antiglycolytic agent, blocking the breakdown of glucose after collection. To prevent clotting while keeping the sample suitable for plasma glucose testing, it is paired with an anticoagulant. The combination used with lithium iodoacetate is lithium heparin, which provides anticoagulation compatible with this antiglycolytic agent. The other additives listed serve different roles or are paired with different inhibitors (for example, fluoride is a glycolysis inhibitor typically used with oxalate, not with lithium iodoacetate; EDTA and potassium oxalate are separate anticoagulants; fluoride alone isn’t the anticoagulant in this pairing).

Glycolysis inhibition and anticoagulation must work together to preserve a true glucose level in a blood sample. Lithium iodoacetate acts as an antiglycolytic agent, blocking the breakdown of glucose after collection. To prevent clotting while keeping the sample suitable for plasma glucose testing, it is paired with an anticoagulant. The combination used with lithium iodoacetate is lithium heparin, which provides anticoagulation compatible with this antiglycolytic agent. The other additives listed serve different roles or are paired with different inhibitors (for example, fluoride is a glycolysis inhibitor typically used with oxalate, not with lithium iodoacetate; EDTA and potassium oxalate are separate anticoagulants; fluoride alone isn’t the anticoagulant in this pairing).

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