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Multiple Choice

Which additive is combined with sodium fluoride in the gray top tube to preserve glucose?

Glucose preservation in gray-top tubes relies on two functions: inhibiting glycolysis and preventing clotting. Sodium fluoride inhibits glycolysis, slowing the consumption of glucose after blood collection. To keep the sample either plasma or whole blood un-clotted for accurate glucose measurement, an anticoagulant is paired with it. The anticoagulant used in gray-top tubes is potassium oxalate, which prevents clotting. The other additives listed belong to different tube types: lithium heparin is used with green-top tubes for plasma chemistry, sodium citrate is used with blue-top tubes for coagulation studies, and EDTA is used with lavender-top tubes for hematology. So, the additive combined with sodium fluoride in the gray top tube to preserve glucose is potassium oxalate.

Glucose preservation in gray-top tubes relies on two functions: inhibiting glycolysis and preventing clotting. Sodium fluoride inhibits glycolysis, slowing the consumption of glucose after blood collection. To keep the sample either plasma or whole blood un-clotted for accurate glucose measurement, an anticoagulant is paired with it. The anticoagulant used in gray-top tubes is potassium oxalate, which prevents clotting. The other additives listed belong to different tube types: lithium heparin is used with green-top tubes for plasma chemistry, sodium citrate is used with blue-top tubes for coagulation studies, and EDTA is used with lavender-top tubes for hematology. So, the additive combined with sodium fluoride in the gray top tube to preserve glucose is potassium oxalate.