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Multiple Choice

Proteins make up about what percentage of the RBC membrane?

Proteins account for about half the red blood cell membrane by weight, reflecting how essential a robust network of membrane and cytoskeletal proteins is for RBC shape and durability. The membrane is a phospholipid bilayer with many proteins embedded or attached, including the spectrin-ankyrin cytoskeletal framework on the inner surface and various channels and transporters. This substantial protein content provides the elasticity and stability needed as RBCs deform to pass through tiny capillaries. So, roughly 50% is protein. Values like 40% would understate it, while 60% or more would overstate it.

Proteins account for about half the red blood cell membrane by weight, reflecting how essential a robust network of membrane and cytoskeletal proteins is for RBC shape and durability. The membrane is a phospholipid bilayer with many proteins embedded or attached, including the spectrin-ankyrin cytoskeletal framework on the inner surface and various channels and transporters. This substantial protein content provides the elasticity and stability needed as RBCs deform to pass through tiny capillaries. So, roughly 50% is protein. Values like 40% would understate it, while 60% or more would overstate it.