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Multiple Choice

Interpret RPI result of 2

RPI shows how well the bone marrow responds to anemia by correcting the reticulocyte percentage for how anemic you are and how long reticulocytes take to mature. When the marrow is responding appropriately, the RPI is typically above about 3, reflecting a brisk reticulocytosis. An RPI around 2 is below that level, indicating an inadequate bone marrow response to the anemia. This does not reflect normal erythropoiesis in the sense of a robust, compensatory rise, nor does it describe marrow cellularity. So an RPI of 2 is interpreted as an inadequate marrow response to anemia.

RPI shows how well the bone marrow responds to anemia by correcting the reticulocyte percentage for how anemic you are and how long reticulocytes take to mature. When the marrow is responding appropriately, the RPI is typically above about 3, reflecting a brisk reticulocytosis. An RPI around 2 is below that level, indicating an inadequate bone marrow response to the anemia. This does not reflect normal erythropoiesis in the sense of a robust, compensatory rise, nor does it describe marrow cellularity. So an RPI of 2 is interpreted as an inadequate marrow response to anemia.